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Le Saux, Olivier
One or more keywords matched the following items that are connected to Le Saux, Olivier
Item TypeName
Concept Multidrug Resistance-Associated Proteins
Academic Article Serum factors from pseudoxanthoma elasticum patients alter elastic fiber formation in vitro.
Academic Article HNF4alpha and NF-E2 are key transcriptional regulators of the murine Abcc6 gene expression.
Academic Article Heterozygosity for a single mutation in the ABCC6 gene may closely mimic PXE: consequences of this phenotype overlap for the definition of PXE.
Academic Article Vitamin K does not prevent soft tissue mineralization in a mouse model of pseudoxanthoma elasticum.
Academic Article Quantification of the calcification phenotype of Abcc6-deficient mice with microcomputed tomography.
Academic Article ABCC6 is a basolateral plasma membrane protein.
Academic Article Analysis of pseudoxanthoma elasticum-causing missense mutants of ABCC6 in vivo; pharmacological correction of the mislocalized proteins.
Academic Article The level of hepatic ABCC6 expression determines the severity of calcification after cardiac injury.
Academic Article Novel deletions causing pseudoxanthoma elasticum underscore the genomic instability of the ABCC6 region.
Academic Article A mouse model of ?-thalassemia shows a liver-specific down-regulation of Abcc6 expression.
Academic Article Expression and in vivo rescue of human ABCC6 disease-causing mutants in mouse liver.
Academic Article Pseudoxanthoma elasticum: cardiac findings in patients and Abcc6-deficient mouse model.
Academic Article Functional Rescue of ABCC6 Deficiency by 4-Phenylbutyrate Therapy Reduces Dystrophic Calcification in Abcc6-/- Mice.
Academic Article The ABCC6 Transporter: A New Player in Biomineralization.
Academic Article Alteration of Extracellular Nucleotide Metabolism in Pseudoxanthoma Elasticum.
Academic Article Pathogenic variants in the ABCC6 gene are associated with an increased risk for ischemic stroke.
Academic Article ABCC6 Deficiency Promotes Development of Randall Plaque.
Academic Article Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice.
Academic Article Oral administration of pyrophosphate inhibits connective tissue calcification.
Academic Article Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).
Academic Article DNA methylation and Sp1 binding determine the tissue-specific transcriptional activity of the mouse Abcc6 promoter.
Academic Article ABCC6 deficiency promotes dyslipidemia and atherosclerosis.
Academic Article ABCC6, Pyrophosphate and Ectopic Calcification: Therapeutic Solutions.
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  • Multidrug Resistance Associated Proteins
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